
Publications
The science behind the breakthroughs
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Central Dogma Cycle and Network: A Model for Cell Memory
Schiller MR
arXiv (2025) 2506:16374
https://doi.org/10.48550/arXiv.2506.16374
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New Gain-of-Function Mutations Prioritize Mechanisms of HER2 Activation
Giacoletto CJ, Valente LJ, Brown L, Patterson S, Gokhale R, Mockus SM, Grody WW, Deng H-W, Rotter JI, Schiller MR.
MedRxiv (2025)
https://doi.org/10.1101/2025.03.03.25323043; PMID: 40093211
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The Gigaassay: A Combined High Throughput and Highly Accurate Platform for Variant Classification
Giacoletto CJ, Valente LJ, Brown L, Patterson S, Gokhale R, Mockus SM, Grody WW, Deng H-W, Rotter JI, Schiller MR.
SSRN (2025)
http://dx.doi.org/10.2139/ssrn.5251898
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Synonymous Variants of Uncertain Silence
Giacoletto CJ, Rotter JI, Grody WW, Schiller MR.
Int. J. Mol. Sci. (2023) 24: 10556
https://doi.org/10.3390/ijms241310556; PMID: 37445732
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The History and Conceptual Framework of Assays and Screens.
Giacoletto CJ, Schiller MR.
Bioessays (2023) 45:e2200191
https://doi.org/10.1002/bies.202200191; PMID: 36789580
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Derbel H, Giacoletto CJ, Benjamin R, Chen G, Schiller MR, Liu Q.
Int J Mol Sci. (2023) 24:6138
https://doi.org/10.3390/ijms24076138; PMID: 37047108
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Most Synonymous Allelic Variants in HIV Tat are Not Silent.
Giacoletto CJ, Benjamin R, Deng HW, Rotter JI, Schiller MR.
Genomics (2023) 115:110603
https://doi.org/10.1016/j.ygeno.2023.110603; PMID: 36893872
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Heligenics: Fulfilling the Promise of the Functional Genome to Enable Precision Medicine
Schiller, MR. (2023) March
Biopharma Dealmakers Issue of Nature. Invited Advertisement
ISSN 2730-6283
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Data Supporting a Saturation Mutagenesis Assay for Tat-driven Transcription with the GigaAssay
Benjamin R, Giacoletto CJ, FitzHugh ZT, Eames D, Buczek L, Wu X, Newsome J, Han MV, Pearson T, Wei Z, Banerjee A, Brown L, Valente LJ, Shen S, Deng HW, Schiller MR.
Data in Brief (2022) 45:108641
https://doi.org/10.1016/j.dib.2022.108641; PMID: 36426049
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GigaAssay – An Adaptable High-throughput Saturation Mutagenesis Assay Platform
Benjamin R, Giacoletto CJ, FitzHugh ZT, Eames D, Buczek L, Wu X, Newsome J, Han MV, Pearson T, Wei Z, Banerjee A, Brown L, Valente LJ, Shen S, Deng HW, Schiller MR.
Genomics (2022) 114(4):110439
https://doi.org/10.1016/j.ygeno.2022.110439; PMID: 35905834
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GigaAssay – a high-throughput assay system for molecular functions and cell processes
Schiller MR, Benjamin R, Giacoletto CJ, FitzHugh ZT, Eames D, Buczek L, Wu X, Newsome J, Han MV, Pearson T, Wei Z, Banjeree A, Shen S, Deng HW. Schiller MR
Research Square (2021)
doi: 10.21203/rs.3.rs-708936/v1
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